Question

tumor suppressor genes can act by making proteins that

Answer 1

Tumour suppressor genes encode protiens that regulate cell cycle. They act as brakes to cell division and inhibit cell proliferation, promote apoptosis,particicpste in DNA repair and act as receptors for hormones. Protein encoded by tumour suppressor gene RB regulates cell through cell cycle. It acts as a brake in G1 phase wand blocks activity of protiens that promote cell to enter into S phase thereby monitoring cellular activities during cell cycle.

An9ther tumour suppressor gene P53 functions as c3ll checkpoint during cell cycle and blocks progression of cell.cycle in G1 phase if DNA damage occurs in the cell so that cell gets time to repair DNA damage before it can proceed to S phase.