Question

Multiple Choice Please answer all 3 no need to go in Depth

Which of the following would be most likely to lead to cancer?

		failure of a proto-oncogene to produce a protein and amplification of a tumor-suppressor gene
		hyperactivity of both a proto-oncogene and a tumor-suppressor gene
		failure of both a proto-oncogene and a tumor-suppressor gene to produce proteins
		amplification of a proto-oncogene and inactivation of a tumor-suppressor gene
		hyperactivity of a proto-oncogene and activation of a tumor-suppressor gene

How do cells become differentiated?

		Different genes are expressed so that different proteins are produced.
		The DNA in each cell changes so that the appropriate proteins are produced.
		Through the process of mitosis
		Some cells contain maternal chromosomes and some contain paternal chromosomes.
		Paternal effect genes begin the process of differentiation by providing positional information.

How do master regulatory genes function in cell differentiation?

		They may produce proteins that stimulate production of more of the master regulatory gene.
		They produce proteins that act as transcription factors to produce proteins specific to the function of the particular cell type.
		The transcription factors they produce coordinately control related genes.
		They are often capable of changing some fully differentiated cells of different types into their particular cell type.
		All of the above

Answer 1

1) Option 5 is the correct answer, Mutations in protooncogenes can lead to an increase in protein expression, hyperactivity and/or loss of regulation. This mutated form is called oncogene. Another   mechanism leading to tumor proliferation is a mutation of antiproliferative tumor-suppressor genes

2)Option 1 is the correct answer, Different genes are expressed so that different proteins are produced. The DNA in each cell changes so that the appropriate proteins are produced. Paternal effect genes begin the process of differentiation by providing positional information

3)Option 5 , all the above is the answer