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what is the role of protooncogenes and tumor suppressor genes in normal cell cycle regulation and...

what is the role of protooncogenes and tumor suppressor genes in normal cell cycle regulation and cancer ?
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  1. Protooncogenes is a gene which altered by mutation . Protooncogenes have many functions in the cell like providing signels that lead to cell division . Many protooncogenes regulate programmed cell death.
  2. In cancer normally help in cell growth . When it changes there are many copies of it . It becomes a bed gene that can permanently turned on or activates when it is not supposed to be. When this happens cell growth become out of control and it leads to cancer.
  3. Tumor suppressor genes are segment of dna that code for negative regulated proteins. It keep the cell from undergoing uncontrol division . Mutated p53 genes are believed to be responsible for causing tumour. So because of this genes cell cycle become uncontrolled and too much growth of cells causes cancer
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