Question

Tumor suppressor genes are most likely to result in cancer through:

A. loss of function mutations

B. gain of function mutations

C. overexpression

D. proto-oncogene formation

Please explain each choice, in particular A and C because I feel they are both correct.

Answer 1

I believe the correct answer to be:

Option A) Loss of function mutation.

As tumor supressor genes are those genes that control the cell cycle or stop the cell from dividing uncrontollably so stopping the function of such enzymes would most likely result in continuously dividing cell.
Option C should not be included because increasing the expression of tumor supressor genes would still maintain their function even at higher quantity.

feel free to leave a comment down below for any further query. good rating would be appreciated if you find my answer helpful. thank you.