Question

Explain what takes place during the Chloride Shift at the pulmonary capillaries of the lungs and...

Explain what takes place during the Chloride Shift at the pulmonary capillaries of the lungs and why this is important.

Homework Answers

Answer #1
  • It is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO3−) and chloride (Cl−) across the membrane of red blood cells (RBCs).
  • A rise in intracellular bicarbonate causes chloride intake and bicarbonate export. The term "chloride shift" refers to this exchange.
  • As a result, blood chloride concentration is lower in systemic venous blood than in systemic arterial blood or in pulmonary circulation because the levels of CO2 and therefore bicarbonate are higher in systemic venous blood, providing less of a driving force for exchange.
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