how does changing the GFR affect NA+ concentration in the distal convoluted tubule?
ANSWER: Macula densa in the kidney acts as sensing agent for increase in the concentration of sodium chloride in the renal tubules. When the sodium chloride level is increased it is suggestive of high glomerular filtration rate and when the Nacl level is decreased in the tubules it suggests that the glomerular filtration is low. When the gfr is decreased there will be less amount of fluid to be filtered subsequently there will be decrease in the amount of sodium that it carries. When gfr is increased viceversa happens. By this gfr affects the sodium concentration in distal convoluted tubule.
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