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Define what is meant by pure, osmotically free water. Considering the distal convoluted tubule of the...

Define what is meant by pure, osmotically free water. Considering the distal convoluted tubule of the amphibian nephron, explain how changes in the permeability of the tubule wall to water affect the amount of pure, osmotically free water excreted in the urine.

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Pure osmotically free water is the water present in urine where it is not need to be present for the solutes to be excreted. And amphibian to excrete solutes there need some amount of water to make it isosmotic with blood plasma

In amphibian the distal convoluted tubule permiability is altered to determine the amount of H2O is ralationto the solutes present in tubule. If the wall is made permiable to water the osmotic equilibrium is reached with the tubular fluid and blood plasma. But this reduces the pure osmotically free water. If if the permeability to the wall is poorly maintained then the the water to solute ratio will be much high and the water required for solutes to be excreted. so there will be the excretion of more pure osmotically free water

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