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how to synthisis choline?

how to synthisis choline?

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Choline is recursor for eurotransmitter acetylcholine, which is involved in the many functions including the memory and muscle control.The Choline was first isolated by the Adolph Strecker from the pig and the ox bile in 1862.When it was the first chemically synthesized by the Oscar Liebreich in 1865,it was known as the neurine. In 1898 neurine was shown to be the chemically identical to choline.Then in 1998, The choline was classified as an essential nutrient by U.S. Food and Nutrition Board of the Institute of Medicine.

The Choline and its metabolites serve three type purposes: structural integrity and the signalingroles for the cell membranes, cholinergic neurotransmission , and a source for the methyl groups via itsmetabolite, trimethylglycine (betaine), which participates in biosynthesis of

S-adenosylmethionine (SAM).

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