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Phosphatidylcholine is a phospholipid in which the phosphate group is esterified to the –OH group of...

Phosphatidylcholine is a phospholipid in which the phosphate group is esterified to the –OH group of the number 3 carbon on glycerol, and is also esterified to the –OH group of choline, HO-CH2-CH2-N+(CH3)3. What is the net charge on phosphatidyl choline in aqueous solution at pH 7?

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Answer #1

Phosphatidylcholine is a molecule having an additional +Ve charged group, choline, at phosphate head group of phosphatidic acid. where, choline is an N,N,N-trimethylethanolammonium cation.

When choline binds to phosphatidic acid, the phosphate group loses one of its negative charges,and makes phosphotidylcholine a neutral molecule so the net charge of phosphatidyl choline is zero.

Positive charge on the choline and a negative charge on the phosphate. For reference attached herewith structure of molecule.

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