Question

Why does factor ix have the same catalytic triad in the amino acid structure as chymotrypsin...

Why does factor ix have the same catalytic triad in the amino acid structure as chymotrypsin but it is located at a different place in the amino acid sequence?

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Answer #1

The factor ix have the same catalytic triad in the amino acid structure as chymotrypsin but it is located at a different place in the amino acid sequence of the protein, due to folding, they will be very close to one another in the heart of the enzyme. The particular geometry of the triad members are highly characteristic to their specific function: it was shown that the position of just four points of the triad characterize the function of the containing enzyme

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