Question

1- why can't a nucleoside be added to a growing nucleic acid chain?

2- how does understanding of proteins and enzymes help to explain how aspirin works?

3- what type of amino acid side chains would you expect to find on the surface of a protein embedded in the lipid-rich environment of a cell membrane?

4- which protein structure is not destroyed by denaturation

Answer 1

1. Nucleoside cannot be added to a growing nucleic acid chain because it does not have phosphate group.

2. Enzymes are biological molecules (proteins) which are specific and works with only certain substrate. Like this aspirin also has a precise chemical mechanism by which it stops pain as well as inflammation. It inhibits an enzyme that produces prostaglandins.

3. Hydrophobic amino acids side chains are found on the surface of a protein embedded in the lipid rich environment of a cell membrane.

4. The primary structure of the protein remains the same after denaturation.