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what is the significance of the presence of cancer stem cells in a tumor as treatment...

what is the significance of the presence of cancer stem cells in a tumor as treatment of the cancer is attempted?

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The cancer stem cells are pluripotent in nature and are also known to cause development of tumor, proliferation of cells and metastatic dissemination. They are the cells which are known to show resistance towards chemotherapy and radiotherapy. On being promoted to such cancer stem cells, it is possible that even the non-tumor cells might become cancerous in nature. Stem cells have been used as one of the best means of imparting cancer therapy due to high totipotency as well as longer span of life. The cancer stem cells are group of cells present in the tumour which has a potential to initiate tumour. The cancer stems cells do not show any kind of resistance to the increasing cell numbers. The cancer cell is able to generate large number of progeny and with self uncontrolled proliferation, it becomes significant in its ability to resist chemotherapy.

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