Please list and describe TWO similarities and TWO differences between stem cells and cancer cells. *Include details about the underlying cellular processes that lead to the similarities. In other words, WHY do the two cell types share common traits even though they are so different?
Answer
Similarities between stem cells and cancer cells are:
Stem cells | Cancer cells |
Stem cells can proliferate indefinitely or self renewal | Cancer cells can also proliferate indefinitely or self renewal |
Express telomerase enzyme for replication of telomeric ends | Cancer cells also have telomerase enzyme |
Resistant to apoptosis (programmed cell death mechanism) | Resistant to apoptosis (programmed cell death mechanism) |
Differences between stem cells and cancer cells are:
Stem cells | Cancer cells |
Tissue regeneration | Tumor development |
Exhibit the properties to differentiate (Multipotent) | Cannot differentiate into every cell of the body |
Stem cells expresses SOX2, Oct-4 genes | Do not expresses these genes |
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