Which of the following sequences can be found in the core promoter of RNA polymerase II? Select all that apply.
Group of answer choices (More than one answer)
a) Inr
b) Enhancer
c) BRE
d) DPE
Ans : a)Inr c)BRE and d) DPE
Initiation element (Inr) is found next to Tata box in eukaryotic promoters and are involved in helping the initiation of transcription by RNA polymerase in the absence of TATA box.
B- recognition element (BRE) is found before TATA box in eukaryotes. It is composed of 7 nucleotide, it helps to recruit RNA polymerase In due to the binding of transcription factor II
Downstream recognition element (DPE) is found in the promoter region after the initiator. It is recognised by transcription factor IID and helps in the recruitment of RNA polymerase II.
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