Question

In prokaryotes, repressors work in all of the following ways EXCEPT:

• A. Interacting with RNA polymerase and inhibiting transition to the open complex
• B. Binding to a sequence overlapping the promoter to prevent RNA polymerase from binding
• C. Recruiting repressive histone modification enzymes
• D. Binding tightly to polymerase and preventing promoter escape

Answer 1

Answer- C. Recruiting repressive histone modification enzymes

Prokaryotes lack histones proteins.

In the following ways

i) repressors join with the promoter nearby sites to prevent the binding of RNA polymerase

ii) repressors bind to the promoter with RNA polymerase, preventing its change from closed to open complex, and preventing promoter to leave the complex ;

iii) repressors bind 3′ of the initiation site and it is inhibited.

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