Question

what is the different between processing and presentation of antigen presenting cells

what is the different between processing and presentation of antigen presenting cells

Homework Answers

Answer #1

Antigen-presenting cells (APCs) are specialised cells (dendritic cells, macrophages and B cells) that can capture, process and present antigen to activate T cells.

Antigen processing:

Antigen processing is the generation of peptide (from antigen) which can bind MHC molecules for presentation to T cells.

Intracellular enzymes degrade antigenic macromolecules into short fragments, which then bind major histocompatibility complex class I and class II molecules.

Antigen presentation:

Antigen presentation is the presentation of antigen as peptide by cell-surface MHC molecules of APCs.

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