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One large pre-B-cell gives rise to multiple B cells with different antigen specificities? Explain how.

One large pre-B-cell gives rise to multiple B cells with different antigen specificities? Explain how.

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Answer #1

The dividing cells are larger than resting cells, this stage is known as larger preB cell.The larger pre-B cell can follow proliferationto form small pre B-cell and to immature Bcell ImmatureB cells are very sensitive to antigen binding, so if they bind self antigen in the bone marrow.

Surface Ig can also be found in M chain in pre-B receptor.Larger pre-B cell gives rise to multiple Bcell such as Small per-B cell, immature B cell and and finally mature B cell. with different antigen specificity.Ig ab expression is found in larger pre Bcell, mature, small pre B cell, immature B cell and mature B cell.Surface Ig present in m-chain in the cytoplasm and on the surface of small pre B cell.Membrane IgM present on the immature B cell.Membrane IgM and IgD present on mature B cell.

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