Question

The clonal selection theory states that

Multiple Choice

• B cells can become T cells by appropriate selection.

• some T cells can produce antibodies by selection.

• B cells that recognize a given epitope multiply to form a family of identical cells.

• macrophages multiply to form a clone.

• cell-mediated immunity depends on processing and presentation of antigen.

Answer 1

The clonal selection theory states that: B cells that recognize a given epitope multiply to form a family of identical cells.

According to clonal selection theory, B cells are activated on recognizing a specific epitope attached to any antigen. These activated B cells then multiply into identical clone cells that are capable of secreting antibody specific to that epitope. B cells multiply into plasma cells that actively secrete antibodies and some plasma cells transform into memory cells that can produce antibodies in case of secondary infection by the same antigen. B cells and T cells are differentiated cells and cannot transform into each other. T cells can help in B cell activation, however, they themselves do not secrete antibody. Macrophages do not form clones and Cell mediated immunity is dependant on T cells, not B cells.