Question

Which statements are false about antigen presentation?
i. Antigen-loaded MHC I educates CD8+ T cells
ii. Phagocytosis results exclusively in presentation to CD4+ T cells
iii. Antigen presenting cells are required for antigen-specific T cell activation
iv. Peptide loading onto MHC-II occurs when it is expressed on the cell surface
v. A viral infection would result in viral antigen presentation on MHC I

	i, iii
	ii, iv
	ii, iii ,iv
	v
	None of the above

Answer 1

The correct answer is option e - None of the above.

Explanation: All of the sentences are true . Antigen which is bound to MHC-I activates CD8+ T cells and for T-cell activation , antigen presentation is very much required. MHC-II molecules bound with peptide are expressed on the cell surface. After entering virus, viral antigens are processed and expressed on the cell surface bound with MC-I molecules which activates immune response against them. So, all of the statements are correct.