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What is the difference between NAD+/NADH and FAD+/FADH2?

What is the difference between NAD+/NADH and FAD+/FADH2?

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Answer #1
  • NAD is nicotinamide adenine dinucleotide and FAD is flavin adenine dinucleotide
  • NAD is used as coenzyme whereas FAD is considered as a cofactor used in redox reactions.
  • FAD can accommodate two hydrogens whereas NAD can accept only one hydrogen
  • The reduction of NAD leads to the formation of NADH+ in glycolysis and Kreb's cycle whereas reduction of FAD leads to the formation of FADH2 in Kreb's cycle
  • During electron transport chain, 3 ATPs are produced from a single molecule of NAD whereas only 1.5-2 ATPs are generated from a molecule of FAD
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