Question

Why are males with the fragile X mutation more affected than females?

Answer 1

I believe the correct answer to be:

Because males only have one copy of X chromosome as their sex chromosomes are XY and if there is a mutation in X chromosome, the male organism will show its defected phenotype.
Females on the other hand have 2 copies of the X chromosome as their genotype is XX so even if one cope is defected, there is one copy that functions properly.

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