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Relate biological manifestations of complement activation to generation of specific complement products.

Relate biological manifestations of complement activation to generation of specific complement products.

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  1. Step1- Complementary products are those which contribute to regulate protiens which are present in the normal human and rodent eye. Complement activation and its regulation are done by ocular complement regulatory protien which contribute to the different patology of various ocular diseases including keratitis, uvetitis and age related muscular degeneration.
  2. Step2- there are some Recombinant forms of naturally ocurring complement regulatory protiens have been exploited in the animal models for treatment of the ocular diseases
  3. Step3- complement activation is a well recognised mediator for myocardial ischaemia reperfusion injury and also for cardiomyocites are well known source for central component i.e c3 whose activation cause inflamation , cell death and profibrotic signalling these can only be detected from there active sites via photon emission technique
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