Question

describe the bacterial RNA Polymerase structure.

Answer 1

In bacteria, only one type of RNA polymerase present that responsible for synthesis all different types of RNA. Bacterial RNA polymerase is a multisbunit enzyme, made up of five different polypeptide-, , ', , and .This Holoenzyme can be seperate into two components, a core enzymes and the sigma factors () . The complete RNA polymerase has molecular mass of ~465KDa.The sigma factors play important role in promoter recognition. Alpha subunit bind with promoter, whereas beta subunit involved chain elongation or act as a catalytic center.