Question

WHY ARE DIFFERENT ANTIBIOTICS USED FOR GRAM -POSITVE AND GRAM- NEGATIVE BACTERIA

Answer 1

This is because the cellular structure and requirements of gram positive and gram negative bacterias are different.

In gram negative bacterias , there is a single layer of peptidoglycan. There is an outer layer of lipopolysaccharides .

In gram positive bacteria, The outer layer is absent , unlike the gram negative bacteria. the peptodoglycan layer is thick.

The antibiotics are made accordingly to destoys the cell walls of the bacterias.

So the antibiotics for the gram positive will destroy peptidoglycan, and the antibiotics for the gram negative bacteria will destroy lipopolysaccharide layer more predominantly.