Question
3) The Zika virus occurs primarily in South and Central America, where it is spread among...
3) The Zika virus occurs primarily in South and Central America, where it is spread among humans primarily by mosquitos. One study investigated whether point mutations in the human hemoglobin gene might influence a person's susceptibility to infection by the Zika virus (like it does for malaria), as compared to the non-mutant hemoglobin gene. To do so, researchers took blood samples from 40 people that varied in these point mutations (10 S-type, 10 C-type, 10 E-type, 10 control) and measured the number of Zika infected red blood cells per microliter. Do any of the hemoglobin mutations (S, C, or E) confer significantly different resistance to Zika as compared to the non-mutant control?
| Trt. Group | # infected cells |
| Hemoglobin S | 1 |
| Hemoglobin S | 0 |
| Hemoglobin S | 0 |
| Hemoglobin S | 3 |
| Hemoglobin S | 7 |
| Hemoglobin S | 6 |
| Hemoglobin S | 9 |
| Hemoglobin S | 7 |
| Hemoglobin S | 0 |
| Hemoglobin S | 2 |
| Hemoblogin C | 11 |
| Hemoblogin C | 18 |
| Hemoblogin C | 17 |
| Hemoblogin C | 11 |
| Hemoblogin C | 3 |
| Hemoblogin C | 9 |
| Hemoblogin C | 18 |
| Hemoblogin C | 20 |
| Hemoblogin C | 15 |
| Hemoblogin C | 20 |
| Hemoglobin E | 3 |
| Hemoglobin E | 15 |
| Hemoglobin E | 23 |
| Hemoglobin E | 13 |
| Hemoglobin E | 21 |
| Hemoglobin E | 25 |
| Hemoglobin E | 15 |
| Hemoglobin E | 31 |
| Hemoglobin E | 125 |
| Hemoglobin E | 28 |
| Control | 50 |
| Control | 25 |
| Control | 61 |
| Control | 36 |
| Control | 22 |
| Control | 19 |
| Control | 29 |
| Control | 40 |
| Control | 41 |
| Control | 39 |
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