Using a table to compare the advantages and disadvantages of using sublimation vs column chromatography techniques for caffeine purification
Technique for the purification of caffeine | Advantage | Disadvantage |
Sublimation | Fast and easy because during the sublimation, only the solid caffeine will convert into the gas phase but not impurity present in it, as a result, you will get the caffeine with high purity. | Costly process because sublimation requires special equipment and vacuum pump |
Column chromatography | Economically cheap (Cost effective) because you need only a glass column and solvent (eluent) to run the column for getting pure caffeine. | Slow process because it consumes a lot of time for caffeine to elute from the column as it has 4 nitrogens and 2 oxygens which can easily bind to stationary phase and retain there. |
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