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Most phase II reactions require a cofactor - what is the definition of a cofactor? (Topic:...

Most phase II reactions require a cofactor - what is the definition of a cofactor? (Topic: Pharmacology: Drug Metabolism)

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In pharmacology nonproptien substance of certain enzymes is known as " Cofactor"

This cofactor component can be inorganic metallic ions or nonprotien complex organic molucules( co enzymes).

example of cofactor with metal ion: cupric: cytochromeoxidase

manganese: Arginase

magnesium: Hexokinase

example of cofactor organic: Thaimine( vitamine B1), Cobalamine, biotine.

cofactors are also known as helper molecules for their assistance in bilogical transformations in enzyme reactions or activities.

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