Question

What is the role of vitamin B12? How is vitamin B12 absorbed?

What is the role of vitamin B12? How is vitamin B12 absorbed?

Homework Answers

Answer #1

Th vitamin B12 is also called cobalamin. It is a water soluble vitamin playing a key role in the red blood cell production from the bone marrow, proper function of the nervous system and DNA synthesis in the body. Vitamin B12 serves as a cofactor during the synthesis of DNA and in the production of amino acids and fatty acids in the body. It plays a key role in the synthesis of myelin and thus important for the proper functioning of the nervous system. It also helps in the maturation process during the red blood cell development.

The vitamin B12 is absorbed via specific intestinal mechanism involving an intrinsic factor. The ingested vitamin B12 if it is in a free form, it will bind with a carrier protein called R-binders. These R-binders are secreted by salivary glands and the mucosal cells of the stomach. If the vitamin is ingested in a protein bound form, the gastric proteolytic enzymes cleaves the protein and the vitamin B12 binds with the R-binder present in the stomach. When the Vitamin B12 - R binder complex reaches the second segment of the duodenum, the proteases secreted by pancreas degrade the R-binder from the complex. Further, the free vitamin B12 binds with intrinsic factor and it passes to ileum. The intrinsic factor protects the vitamin from the degradation by the intestinal microbes. Ileum is a part of small intestine where it recognizes the Vitamin B12 - intrinsic factor complex and the vitamin B12 is absorbed.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
How do vitamin B12 and folate function similarly in the body? Why is it important to...
How do vitamin B12 and folate function similarly in the body? Why is it important to avoid high doses of either of these two vitamins? And a credible information to support your Answer.
Vitamin B12 and folic acid are required for nuclear maturation, since they are important for DNA...
Vitamin B12 and folic acid are required for nuclear maturation, since they are important for DNA synthesis Discuss how the body use them for DNA synthesis?
the home health nurse is to administer 0.5mg of vitamin b12 1000 mcg/ml intramuscular injection daily...
the home health nurse is to administer 0.5mg of vitamin b12 1000 mcg/ml intramuscular injection daily for 5 days. the drug supply available is a 30ml containing vitamin b12 1000 mcg/ml.how many milliliters should the nurse draw up in the syringe?
Other than vitamin B12, which two water-soluble vitamins are important for healthy functioning of the nervous...
Other than vitamin B12, which two water-soluble vitamins are important for healthy functioning of the nervous system?
1) Vitamin B12, cyanocobalamin, is essential for human nutrition.   Its molecular formula is C63H88CoN14O14P. A lack...
1) Vitamin B12, cyanocobalamin, is essential for human nutrition.   Its molecular formula is C63H88CoN14O14P. A lack of this vitamin in the diet can lead to anemia. Cyanocobalamin is the form of the vitamin found in vitamin supplements. What is the mass of 1.0 × 1010 molecules of cyanocobalamin? g 2) Dimethylnitrosamine (CH3)2N2O is a carcinogenic (cancer causing) substance that may be formed in foods, beverages or gastric juices from the reaction of nitrate ion (used as a food preservative) with...
How does bone serve as a "calcium bank" for the body? Describe the role of vitamin...
How does bone serve as a "calcium bank" for the body? Describe the role of vitamin D and specific hormones in making “deposits” and “withdrawals” from the calcium bank.
⦁   Folate and B12 have an important role in hematology (“blood-related” processes) such that a deficiency...
⦁   Folate and B12 have an important role in hematology (“blood-related” processes) such that a deficiency of either of these vitamins can result in anemia. Discuss the interrelationship between these vitamins and why a deficiency of either of them results in megaloblastic anemia. Your answer will likely need to talk to some extent about the methyl trap hypothesis. Make sure to relate any metabolic description of folate and B12 to the basis for anemia resulting from a deficiency.
Individuals with pernicious anemia have low plasma levels of: vitamin B12 RBCs intrinsic factor EPO a...
Individuals with pernicious anemia have low plasma levels of: vitamin B12 RBCs intrinsic factor EPO a and b a, b and c Which of the following statements regarding RBCs is incorrect: an average adult has ~30 trillion RBCs RBCs are doughnut shaped with a hole in the center 1/3 of all the cells in an average adult are RBCs RBCs are anucleate
(4/30) EXPLAIN WHAT IS THE ROLE OF VITAMIN D IN THE REGULATION OF PROTEINS IN RELATION...
(4/30) EXPLAIN WHAT IS THE ROLE OF VITAMIN D IN THE REGULATION OF PROTEINS IN RELATION TO THE CELL CYCLE AND SENESCENCE. [Typed please. (sometimes I can't understand the handwriting in some of the responses I get) ]
How is Vitamin D formed? What is the precursor form of vitamin D?
How is Vitamin D formed? What is the precursor form of vitamin D?
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT