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Would you expect a deleterious allele that enjoys a heterozygous advantage to disappear if the heterozygote...

Would you expect a deleterious allele that enjoys a heterozygous advantage to disappear if the heterozygote advantage is removed?

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Yes. Heterozygous individuals are in advantageous position over either of the homozygous individuals. Take for ex. sickle cell anaemia. The normal individuals ( HbA  / HbA ) suffer from malaria if infected and they may die also and the homozygous recessive individuals( HbS / HbS ) suffer from sickle cell anaemia. But the heterozygous individuals(HbA / HbS ) can resist malaria. Through them, the deleterious allele persist in the population. If the heterozygous advantage is removed, the heterozygous individuals will not survive and with their death, the deleterious recessive allele will also disappear from the population.

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