In humans, the widow’s peak allele is dominant over the straight hairline allele. In a population of humans, the frequency of the allele for a widow’s peak is 0.61 and the frequency of the allele for a straight hairline is 0.39. What would the genotypic frequencies be if the population is in equilibrium? _____ = Frequency of homozygous dominant individuals _____ = Frequency of heterozygous individuals _____ = Frequency of homozygous recessive individuals How many individuals would you expect of each genotype in a population of 75 humans? _____ = Number of homozygous dominant individuals _____ = Number of heterozygous individuals _____ = Number of homozygous recessive individuals
Let, the widow's peak allele be A and straight hairline allele be a and their frequencies be p and q respectively.
The frequency of AA individuals in a population is p2 and that of aa individuals is q2.
Thus, genotypic frequency will be:
p2 + 2pq + q2 =1
(p+q)2 = 1
0.61 + 0.39 = 1
Frequency of homozygous dominant individuals = p2 = (0.61)2 = 0.3721= 37%
Frequency of heterozygous individuals = 2pq = 2 x 0.61 x 0.39 = 0.4758 = 48%
Frequency of homozygous recessive individuals = q2 = (0.39)2 = 0.1521 =15%
In a population of 75 humans,
Number of homozygous dominant individuals = 37% of 75 = 28
Number of heterozygous individuals = 48% of 75 = 36
Number of homozygous recessive individuals = 15% of 75 = 11
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