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Codominance of MHC alleles plays a part in making sure that a diversity of antigens can...

Codominance of MHC alleles plays a part in making sure that a diversity of antigens can be presented by each individual? Explain how?

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MHC alleles are expressed in co dominant pattern. This means each allele is dominant and expressed equally.

They carry 2 alleles of each class 1 genes. So 6 different types of MHC I. HLA - A, HLA - B and HLA-C.

HLA is human leucocyte antigen.

MHC class 1 has HLA A B C. MHC class2 has got HLA 6 D's that is HLA DPA1, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, HLA DRB1.

In MHC class 2 a person inherits a pair of DP producing alfa and beta. A pair of DQ producing alfa and one DRA producing alfa. One or more of DRB. That is 6 or more functioning alleles in MHC class 2.

So heterozygous individuals inheriting one allele from each parent vary highly because of codominance in almost 3 pair of genes. Thus codominance result in high variation of inheritance in individuals, due to diversity of antigens.

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