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If your cells were unable to procure enough niacin, what specific effect would this have on...

If your cells were unable to procure enough niacin, what specific effect would this have on glycolysis?

please it explain the question simply as possible.

Science   Anatomy-And-Physiology   
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Answer #1

Niacin is the generic term used with a broader perspective to represent nicotinic acid and nicotinamide. It is essential for the metabolism of carbohydrates, proteins and fats. It can be synthesized in the body from tryptophan. Niacin is converted into two important coenzymes:-

Nicotinamide adenine dinucleotide (NAD)

Nicotinamide adenine dinucleotide phosphate (NADP)

Out of both, only NAD is used in the process of glycolysis.

NAD is involved in conversion of glyceraldehyde 3 phosphate to 1, 3 bisphosphoglycerate. During this reaction, NAD is also converted into NADH which undergoes Electron Transport Chain, yielding energy by oxidative phosphorylation. But if NAD is deficient, this action cannot occur. This leads to increase in concentration of glyceraldehyde 3 phosphate.

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