For every litre that goes in, a litre comes out. Any imbalance of water coming in and leaving the body creates an osmotic imbalance that will adversely affect the cell and tissue function. Osmotic balance ensures that optimal concentrations of electrolytes and non electrolytes are maintained in cells, body tissues and in interstitial fluid.
Urine formation depends upon Glomerular filtration, Tubular reabsorption and Tubular secretion.
Urine excretion rate = Filtration rate - Reabsorption rate + Secretion rate.
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