Question

Give one example of when a target cell would participate in A) upregulation and B) downregulation

Answer 1

Answer :-A) upregulation =-persistently low levels of a hormone can cause its target cells to form additional receptors for that hormone

ex:-estrogen causes progesterone to produce more receptors when there isn't; enough, enhancing their ability to respond to progesterone

ex. :-insulin up-regulates glucagon when there is not a lot present...

Answer =B. (downregulation) :--prolonged exposure to high hormone concentrations can decrease the no. of receptors of that hormone; desensitizes the target cells, so they response less vigoursly to hormonal stimulation, preventing them from overreacting to persistently high hormone levels

ex:-. progesterone down-regulates estrogen receptors in the uterus, thus antagonizing estrogens actions....thanks dear student