Question

A clinical trial is conducted to test a new medication designed to lower systolic blood pressure...

A clinical trial is conducted to test a new medication designed to lower systolic blood pressure (SBP). Participants are randomly assigned to receive the new medication or a placebo. The outcome is clinically significant SBP reduction after 30 days. The data are shown below. Compute the totals. (1pt)

Significant Reduction in SBP

No Significant Reduction in SBP

Total

New Medication

44

76

Placebo

21

99

Total

  1. Compute the proportion of participants who experienced a significant reduction in SBP, given they received the new medication (1pt):
    1. 0.3667
    2. 0.6769
    3. 0. 6333
    4. 0.175
    5. Some other answer (indicate):

  1. Compute the proportion of participants who experienced a significant reduction in SBP, given they received the placebo (1pt):
    1. 0.825
    2. 0.3667
    3. 0.3231
    4. 0.175
    5. Some other answer (indicate):

  1. Generate a 90% confident interval for the true proportion of people experiencing a significant reduction in SBP given they received the new medication. (4pts)
    1. (0.3635, 0.3699)
    2. (0.2943, 0.4391)
    3. (0.3155, 0.4179)
    4. (0.2684, 0.465)
    5. Some other answer (indicate):

  1. Estimate the risk difference in significant SBP reductions for the participants who received the new medication versus those that received the placebo and indicate your answer: (1pt)
    1. 0.3538
    2. 0.0958
    3. 0.1719
    4. 0.1917
    5. Some other answer (indicate):

  1. Generate a 95% confidence interval for the difference in proportions of participants experiencing a significant reduction in SBP for the participants who received the new medication versus those that received the placebo and indicate your answer: (4pts)
    1. (0.1856, 0.1978)
    2. (0.0819, 0.3015)
    3. (-0.014, 0.2056)
    4. (0.244, 0.4636)
    5. Some other answer (indicate):

  1. True or False: There is a significant difference in the proportions of participants experiencing a significant reduction in SBP for the participants who received the new medication versus those that received the placebo: (1pt)
    1. True
    2. False

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