Question

A clinical trial is conducted to test a new medication designed to lower systolic blood pressure (SBP). Participants are randomly assigned to receive the new medication or a placebo. The outcome is clinically significant SBP reduction after 30 days. The data are shown below. Compute the totals. (1pt)

	Significant Reduction in SBP	No Significant Reduction in SBP	Total
New Medication	44	76	120
Placebo	21	99	120
Total	65	175	240

1. Estimate the risk difference in significant SBP reductions for the participants who received the new medication versus those that received the placebo and indicate your answer: (1pt)
   1. 0.3538
   2. 0.0958
   3. 0.1719
   4. 0.1917
   5. Some other answer (indicate):
2. Generate a 95% confidence interval for the difference in proportions of participants experiencing a significant reduction in SBP for the participants who received the new medication versus those that received the placebo and indicate your answer: (4pts)
   1. (0.1856, 0.1978)
   2. (0.0819, 0.3015)
   3. (-0.014, 0.2056)
   4. (0.244, 0.4636)
   5. Some other answer (indicate):
3. True or False: There is a significant difference in the proportions of participants experiencing a significant reduction in SBP for the participants who received the new medication versus those that received the placebo: (1pt)
   1. True
   2. False

Answer 1