Question

1. A clinical trial is conducted comparing a new antipyretic (fever reducing drug) to a placebo. Participants are randomly assigned to receive the new treatment or a placebo and the outcome is body temperature reduction within 2 hours. The data are shown below.

	Fever Reduction	No Fever Reduction
New Medication	46	37
Placebo	43	40

Is there a significant difference in the proportions of patients reporting fever reduction? Run the test at a 5% level of significance.

Step 1.           Set up hypotheses and determine level of significance

                                   

Step 2.            Select the appropriate test statistic

                               

Step 3.            Set up decision rule

                       

Step 4.            Compute the test statistic

           

           

Step 5.             Conclusion

Answer 1