Question

What is reverse tolerance?

This question is for a narcotics class.

Answer 1

The increased/ elevated positive or negative reaction after the repeated/ consistent drug usage is referred to as reverse tolerance.

This is also termed as drug sensitisation.

Some drugs reflect high reverse tolerance.

It is an antonym for drug tolerance.

Opiates, antidepressants, alcohol and nicotine are the substances that tend to be with higher reverse tolerance.

For example, more consumption of one of the above mentioned substances may cease production of the enzymes in body and damage an organ.