Question

A patient suffers suffering from GERD is prescribed a proton pump inhibitor. Identify and which type of food will not be optimally digested and Explain the chemistry underlying your answer.

Answer 1

Green leafy vegetables and protein containing food digestion will be impaired. As green leafy vegetables contain iron for adoption of active for of iron that is ferric to ferrous form acidic environment is required. In the presence of PPI this will be impaired.

For protein break down pepsinogen in stomach should be activated to active form pepsin. This activation occur only in the presence of acid. So protein containing foods absorption will also be impaired