Question

"Skidmore Mosby's 2020 nursing drug reference ''

Make drug cards for the following medications including:

Drug Name (Generic/Trade):                                  Classification:                                       Action:                                                                       Uses:

Adverse Effect:                                                      Safe Dose:                                                                               

Side Effects:       Nursing Implications:              Treatment of Overdose:

1.Thiazides

2. Furosemide

3. Mephobarbital

3. Phenytoin

4. Amiloride

5. Clonazepam

6. Paramethadione

7.ethosuximide

8. Carbamazepine

9. Oxcarbazepine

10. Carbidopa

11.alprazolam

12. Amitriptyline

13. Marplan

14. Chlorpromazine

15. Methylphenidate

16. Aricept

Answer 1

Generic name	classification	Action	uses	safe dose	adverse effects	side effects	nursing implication	treatment of overdose
thiazide	-diuretic	inhibits reabsorption of sodium (Na+) and chloride (Cl−) ions from the distal convoluted tubules	-Hypertension	-0.5 to 1gram /day	-electrolyte imbalance -sensitivity to sunlight -increase serum uric acid level	-dizziness and lightheadedness, -blurred vision, -loss of appetite, -itching, -stomach upset, -headache, and -weakness.	- check BP -Check electrolytes	-activated charcoal -iv fluids - laxatives
frusemide	loop diuretic	- increase the excretion of Na+ and water by the kidneys by inhibiting their reabsorption from the proximal and distal tubules, as well as the loop of Henle	-hypertension -heart failure	-20 mg to 80 mg /day	- allergy reaction	increased urination, thirst, muscle cramps, itching or rash, weakness, dizziness, spinning sensation, diarrhea,	-electrolyte - ecg -check for bradycardia	-fluids - electrolyte - supportive treat ment like oxygen
Mephobarbital	-barbiturates	- increases the amount of time chloride channels are open, which in turn depresses the central nervous system. This action occurs by acting on GABA-A receptor subunits	-seizures -anxiety	30 to 120 mg/day	-sedation -bradycardia	-lack of energy -depressed mood -sleepiness	-check for vitals and breathing	-activated charcoal -oxygen
phenytoin	-anti epileptic drug	voltage-dependent block of voltage gated sodium channels. This blocks sustained high frequency repetitive firing of action potentials.	-seizures -tumours of brain	5mg/kg/day	-deep sleep - gum hyperplasia	headaches. feeling drowsy, sleepy or dizzy. 3. feeling nervous, unsteady 4. constipation. 5 sore or swollen gums	- watch for breathing -awakefulness	- activated charcoal
Amiloride	-pottassium sparing diuretic	act on the distal tubule of the nephron where it selectively blocks sodium transport, thereby inhibiting sodium-potassium exchange.	-Congestive Heart Failure · Hypertension · Thiazide-Induced Hypokalemia · in Renal Impairment	10 to 40 mg/day		Headache, dizziness, nausea, vomiting, loss of appetite, diarrhea	- watch for hyperkalemia	-stop the drug - calcium gluconate
Clonazepam	-benzodiazepine	-facilitate GABAergic transmission in the brain by a direct effect on benzodiazepine receptors	-status epilepticus	0.1 to 0.2 mg/kg/day	-cognitive impairement	drowsiness dizziness	- shallow breathing -check for hyperactivity	-flumazenil - management of airway, circulation and breathing
paramethadione	- anti epileptic drug	reduce the T-type calcium currents in thalamic neurons which has been proposed to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram (EEG)	absence seizure	5mg/day	-worsening of seizures	-allergic reaction -swollen throat	- pupil monitoring - BP monitoring	-icu treatment -supportive measures
ethosuximide	-anti epileptic drug	partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.	- absence seizures	20 to 40 mg/kg/ day	-dyspnoea -respiratory failure -death	Drowsiness, dizziness, tiredness, headache, stomach upset, loss of appetite, nausea, vomiting, weight loss, diarrhea, or loss of coordination	-check for breathing -usually they are paediatric age group	-hemodialysis -supportive care