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Define and explain differences between ERPF and GFR calculations

Define and explain differences between ERPF and GFR calculations

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Answer #1

Effective renal plasma flow (eRPF) is a measure used in renal physiology[1] to calculate renal plasma flow (RPF) and hence estimate renal function.

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR is inversely proportional to the renal plasma flow! The GFR is used to estimate kidney function and to stage chronic kidney disease.

Parameter Value

renal blood flow RBF=1000 ml/min

hematocrit HCT=40%

glomerular filtration rate GFR=120 ml/min

renal plasma flow RPF=600 ml/min

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