Describe the development of microbial resistance to disinfectants.
Answer - There are different - different groups of bacterias and very sensitive to disinfectants. Gram negative bacteria are less sensitive to disinfectants compare to gram positive bacteria. and become more resistant. There are many cause behind bacteria 's resistant against disinfectant such as -
- Bacterial spore are main cause of development of bacterial resistance because intrinsic resistance found with bacterial spore.
- Reduce permeablity of becterial cell membrane.
- Acquired resistance to disinfectants develop by cellular mutation or changes in the genetic elements.
- If lower strength of disinfectant use to kill microorganism, they become resistant to it.
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