Question

1. What is the selective pressure applied during the mechanism associated with the development of drug resistance by viruses?
   1. The virus
   2. The immune system
   3. The drug
   4. A and B
   5. B and C
2. If PrEP is given to a patient who is already infected with HIV is the risk of selection for drug resistant mutants increased?
   1. Yes
   2. No
3. Why can drug treatments NOT cure HIV?
   1. HIV is resistant to all drugs
   2. HIV maintains a latent viral reservoir
   3. HIV continually reinfects people
   4. All of the above
   5. None of the above
4. If a patient stops taking an antiviral drug why might this lead to the development of drug resistance?
   1. It permits partially resistant strains to survive and continue to adapt in the absence of the drug’s selective pressure.
   2. It permits the virus to replicate at a higher level therefore, increasing the risk of random mutation arising which lead to development of resistance.
   3. It cannot lead to drug resistance as the selective pressure has been removed.
   4. A and B
   5. B and C

Answer 1

Selection pressure can be regarded as a force that causes a particular organism to evolve in a certain direction. A selective pressure is any reason for organisms with certain phenotypes to have either a survival benefit or disadvantage.Selective pressures leads natural selection.

a) the virus:- In the case of drug resistance, drugs cause a selective pressure by killing susceptible bacteria, allowing drug-resistant virus to survive and multiply

2) f PrEP is given to a patient who is already infected with HIV is the risk of selection for drug resistant mutants increased?

ans-Yes,

3) Why can drug treatments NOT cure HIV?

ans)- All the above

4) If a patient stops taking an antiviral drug why might this lead to the development of drug resistance?

ans:- It permits partially resistant strains to survive and continue to adapt in the absence of the drug’s selective pressure.