Question

Which of the following chemicals inhibit platelet adhesion an aggregation? Nitric oxide and prostacyclin Thromboxane A2,...

Which of the following chemicals inhibit platelet adhesion an aggregation?

Nitric oxide and prostacyclin

Thromboxane A2, collagen and epinephrine

Nitric oxide and thromboxante A2

Collagen, epinephrine, and  prostacyclin
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Answer #1

The answer is 1.nitric oxide and prostacyclin

Prostacyclin

It is a very potent endogenous inhibitor of platelet aggregation. It is also a strong vasodilator that inhibits the growth of vascular smooth muscle cells. Prostacyclin inhibits platelet activation induced by several stimulants such as thrombin, collagen, ADP, TXA2, etc.

Nitric oxide

It inhibits platelet adhesion, aggregation, and promotes disaggregation of preformed platelet aggregates. Its effects are mediated by stimulation of guanylate cyclase and the formation of cyclic GMP and its subsequent transduction mechanism.

The other options are not correct answers because rest all chemicals promotes platelet aggregation.

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