Question

Determine the cause of the positive DATs for the patients below: Patient #2: Mom is A...

Determine the cause of the positive DATs for the patients below:

Patient #2:

Mom is A negative with an Anti-D

Baby is A positive, DAT 2+

What antibody could be causing the positive DAT? ______________

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Answer #1

DAT is direct antibody test.Mother and baby have a negative and a positive blood group respectively.Mother's body will produce antibodies against baby's positive blood group. This antibodies can cross into baby's bloodstream and cause the baby's redblood cells to break.

In this case mom is a negative but she received a shot of Rho(D)immunoglobulin during pregnancy to prevent her from making antibodies against her baby's blood.Sometimes this injection can cause the DAT test positive. Another possibility is if the mother has developed ant-d antibodies in a previous pregnancy (she is already sensitized) then these immunoglobulin injections do not help.In this case yhe baby might have positve DAT test.Baby may need phototherapy treatment in DAT 2 positive case.

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