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What is the reaction mechanism for the schiff's base condensation reaction between salicaldehyde and methylamine? Additionally...

What is the reaction mechanism for the schiff's base condensation reaction between salicaldehyde and methylamine? Additionally what is the reaction mechanism between the formed imine and copper acetate in the presence of sodium acetate?

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Answer #1

The reaction of aldehydes and ketones with ammonia or 1º-amines is called Schiff's base condensation. They form imine derivatives, also known as Schiff bases (compounds having a C=N function). Water is eliminated during the condensation, which is acid-catalyzed and reversible. Methanol or tetrahydrofuran (THF) are used in this reaction.

The resulting imine forms a metal complex with copper acetate in the presence of sodium acetate.

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