What is a Schiff base reaction and how does it relate to this template synthesis?
Draw the mechanism for a Schiff base condensation.
Schiff base: the electrophilic carbon of aldehyde or ketones can be attached by amine (RNH2). As a result C = O is replaced by C = N. This is known as Schiff base reaction. PLP liked to ethyne via Schiff base Next step Schiff base transfer is transfer is occurred. PLP is transferred from the from the ethyne lysine to the nitrogen of the amino acid substrate. PLP bond to enzyme via Schiff base free amino acid PLP bound to amino acid via Schiff. Schiff base: the electrophilic carbon of aldehyde or ketones can be attached by amine (RNH2). As a result C = O is replaced by C = N. This is known as Schiff base reaction. PLP liked to ethyne via Schiff base
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