Question

What principle is chromatography based on?

Answer 1

adsorption is the principal for the chromatography

let me explai in detail

if you have a different compounds if you spot on the TLC (thin layer chromato graphy) the moment of these spots on the TLC plate will completely depends on the polarity of the compound

suppose if compound is more opolar this will bind strongly with silica gel of the stationary phase when you rise it it will move slowely

whereas less polar compound will move more because it will less stickky to the silica gel