Question

What is TISAB and what is the purpose of it?Why is “dilution solution” used to make standard solutions? What is the problem with using water to make dilution?

Answer 1

1. A total ionic strength adjustment buffer (TISAB) is a buffer solution which increases the ionic strength of a solution to a relatively high level. This is important for potentiometric measurements, including ion selective electrodes, because they measure the activity of the analyte rather than its concentration.
2. Because there are some salts are having some impurities. Directly if we prepare concentrations by taking weight, that may effect on concentration.
3. 1) Sometimes salts are not soluble in water, to make it clear solution we have to add some additional solvents. 2) water should be free from minerals otherwise that may effect on resulting concentration.