Question

A nucleophilic aromatic substitution (SNAr) reaction will be performed using an aryl fluoride and 4-methoxyphenol. Show...

A nucleophilic aromatic substitution (SNAr) reaction will be performed using an aryl fluoride and 4-methoxyphenol. Show the mechanism

Science   Chemistry   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Benzene ring generally do not give nucleophilic substitution reaction but in the presence of electron withdrawing groups, it undergoes nucleophhilic substitution reaction. we mixed 4-fluorobenzaldehyde, 4-methoxyphenol, potassium carbonate, and dimethyl sulfate and heated mixture for one hour. The product we wish to obtain is 4-aryloxybenzaldehyde by Nucleophilic Aromatic Sustitution.

Your one thumbs up will help me lot. Thanks!

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Explain why electrophilic aromatic substitution reactions on aryl rings meta directing substituents are slower than the...
Explain why electrophilic aromatic substitution reactions on aryl rings meta directing substituents are slower than the same reaction on aryl rings with ortho/para directing substituents.  
List three (3) criteria for nucleophilic aromatic substitution.
List three (3) criteria for nucleophilic aromatic substitution.
How does the intermediate produced in nucleophilic aromatic substitution differ from the intermediate produced in electrophilic...
How does the intermediate produced in nucleophilic aromatic substitution differ from the intermediate produced in electrophilic aromatic substitution? How are the two intermediates similar? Briefly explain.
True or False 1) Nucleophilic substitution reactions occur at alkyl, alkenyl (vinylic), and aromatic carbons bonded...
True or False 1) Nucleophilic substitution reactions occur at alkyl, alkenyl (vinylic), and aromatic carbons bonded to a halide. True False 2) Experiments involving the formation of a carbocation intermediate indicate that gas phase reactions have activation energies comparable to aqueous solutions. The stability of a carbocation is not influenced by surrounding solvent molecules. True False
1.Which of the following would react faster than benzene in an electrophilic aromatic substitution reaction? a....
1.Which of the following would react faster than benzene in an electrophilic aromatic substitution reaction? a. acetophenone b. benzoic acid c. anisole d. chlorobenzene 2.Which of the following would react slower than benzene in an electrophilic aromatic substitution reaction? a. benzaldehyde b. phenol c. toluene d. aniline 3.If an electrophile was added to acetophenone via an electrophilic aromatic substitution, at what position(s) of the ring would the electrophile add? a. ortho b. meta c. ortho d. para only 4.If an...
Why can’t a aldehyde or ketone undergo a nucleophilic substitution reaction? What are these FGs missing...
Why can’t a aldehyde or ketone undergo a nucleophilic substitution reaction? What are these FGs missing that the oxidation state 3+ FGs, such as an ester and carboxylic acid, have?  
Performed Iodination of Salicylamide demonstrating electrophilic aromatic substitution. My suspicion is that this experiment would fail...
Performed Iodination of Salicylamide demonstrating electrophilic aromatic substitution. My suspicion is that this experiment would fail if NaI were substituted with NaCl to makechlorosalicylamide. Explain why the experiment would not be (as) successfulwith NaCl.
The reaction to form 4-nitroacetanilide from the acetanilide by electrophilic aromatic substitution. Nitrating mixture is a...
The reaction to form 4-nitroacetanilide from the acetanilide by electrophilic aromatic substitution. Nitrating mixture is a mixture of concentrated sulfuric acid and concentrated nitric acid. Glacial acetic acid and acetanilide are used. i) For this experiment, a low temperature (< 30 °C) was maintained throughout the addition of the nitrating mixture. What was the main purpose for maintaining a low temperature? ii)How did you (or how could you) confirm that your product was 4-Nitroacetanilide and not some other compound? If...
Dye Coupling, Complete electropholic aromatic substitution mechanisms (SHOW ALL RESONANCE FOR THE INTERMEDIATES FORMED): 1. 4-diazo...
Dye Coupling, Complete electropholic aromatic substitution mechanisms (SHOW ALL RESONANCE FOR THE INTERMEDIATES FORMED): 1. 4-diazo N, N-diethylaniline fluoroborate and resorcinol. 2. 4-diazo N, N-diethylaniline fluoroborate and phloroglucinol. 3. 4-diazo N, N-diethylaniline fluoroborate and 2,4-pentanedione. 4. 4-diazo N, N-diethylaniline fluoroborate and 3-methyl-1-phenyl-2-pyrazolin-5-one. Thanks
the reaction of lithium naphthalene (LiC10H8) with an alkyl fluoride is an sn2 reaction for this...
the reaction of lithium naphthalene (LiC10H8) with an alkyl fluoride is an sn2 reaction for this reaction please 1)draw thw reaction including stereochemistry when/if necessary 2)circle the nucleophillic center in the reaction 3)circle the electrophillic center in the reaction 4)using curved arrows show the flow of electrons for the formation of the reaction product(s)
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT